Scientific Name: Paguma larvata
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia
Summary: The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_0007 | 2021.04 | 10X Genomics | Frontal | Normal | 6593 | Link |
| Vthunter_0008 | 2021.04 | 10X Genomics | Kidney | Normal | 1930 | Link |
| Vthunter_0009 | 2021.04 | 10X Genomics | Liver | Normal | 34029 | Link |
| Vthunter_0010 | 2021.04 | 10X Genomics | Lung | Normal | 12863 | Link |
| Vthunter_0011 | 2021.04 | 10X Genomics | Spleen | Normal | 9682 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in testis (RPKM 31.2), kidney (RPKM 22.6) and 25 other tissues?
